Implications of prion diseases for dentistry: an update.
Identifieur interne : 000390 ( Main/Exploration ); précédent : 000389; suivant : 000391Implications of prion diseases for dentistry: an update.
Auteurs : Bego A Palacios-Sánchez [Espagne] ; Germán C. Esparza-G Mez ; Julián Campo-Trapero ; Rocío Cerero-LapiedraSource :
- Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics [ 1528-395X ] ; 2008.
Descripteurs français
- KwdFr :
- Animaux (MeSH), Bouche (anatomopathologie), Contrôle de l'infection dentaire (méthodes), Distribution tissulaire (MeSH), Humains (MeSH), Instruments dentaires (effets indésirables), Maladies de la bouche (étiologie), Maladies à prions (classification), Maladies à prions (complications), Maladies à prions (transmission), Pulpe dentaire (anatomopathologie), Soins dentaires pour malades chroniques (MeSH), Transmission de maladie infectieuse du patient au professionnel de santé (prévention et contrôle).
- MESH :
- anatomopathologie : Bouche, Pulpe dentaire.
- effets indésirables : Instruments dentaires, Maladies à prions.
- méthodes : Contrôle de l'infection dentaire.
- prévention et contrôle : Transmission de maladie infectieuse du patient au professionnel de santé.
- étiologie : Maladies de la bouche, Maladies à prions.
- Animaux, Distribution tissulaire, Humains, Soins dentaires pour malades chroniques.
English descriptors
- KwdEn :
- Animals (MeSH), Dental Care for Chronically Ill (MeSH), Dental Instruments (adverse effects), Dental Pulp (pathology), Humans (MeSH), Infection Control, Dental (methods), Infectious Disease Transmission, Patient-to-Professional (prevention & control), Mouth (pathology), Mouth Diseases (etiology), Prion Diseases (classification), Prion Diseases (complications), Prion Diseases (transmission), Tissue Distribution (MeSH).
- MESH :
- adverse effects : Dental Instruments.
- classification : Prion Diseases.
- complications : Prion Diseases.
- etiology : Mouth Diseases.
- methods : Infection Control, Dental.
- pathology : Dental Pulp, Mouth.
- prevention & control : Infectious Disease Transmission, Patient-to-Professional.
- transmission : Prion Diseases.
- Animals, Dental Care for Chronically Ill, Humans, Tissue Distribution.
Abstract
Prions are normal proteins present in all mammals, especially in the central nervous system (CNS) and lymphoreticular tissue. Their transformation into a highly infectious molecule gives rise to a group of diseases known as transmissible spongiform encephalopathies (TSEs), which cause vacuolar degeneration of gray matter and produce a fatal neurodegenerative disorder. Prion diseases have attracted considerable attention in recent years, and this review of the literature was designed to determine their implications for dentistry, studying the possibility of cross-transmission in the dental office and describing their oral manifestations. The main oral manifestations are dysphagia, dysarthria, paresthesias, dysesthesias, and dysgeusia. The most frequently involved oral tissues are the trigeminal ganglion, posterior third of the tongue, tonsils, and, much less commonly, alveolar nerves, gingiva, and salivary glands. Although no contagion has been reported in the dental setting to date, prions resist the usual dental sterilization systems and transmission of this type of disease remains a potential risk. It is therefore important for dentists to be aware of these diseases, to identify high-risk patients by obtaining an adequate clinical history, and to know the appropriate procedures to be followed.
DOI: 10.1016/j.tripleo.2007.09.033
PubMed: 18280965
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<term>Mouth (pathology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term>
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<front><div type="abstract" xml:lang="en">Prions are normal proteins present in all mammals, especially in the central nervous system (CNS) and lymphoreticular tissue. Their transformation into a highly infectious molecule gives rise to a group of diseases known as transmissible spongiform encephalopathies (TSEs), which cause vacuolar degeneration of gray matter and produce a fatal neurodegenerative disorder. Prion diseases have attracted considerable attention in recent years, and this review of the literature was designed to determine their implications for dentistry, studying the possibility of cross-transmission in the dental office and describing their oral manifestations. The main oral manifestations are dysphagia, dysarthria, paresthesias, dysesthesias, and dysgeusia. The most frequently involved oral tissues are the trigeminal ganglion, posterior third of the tongue, tonsils, and, much less commonly, alveolar nerves, gingiva, and salivary glands. Although no contagion has been reported in the dental setting to date, prions resist the usual dental sterilization systems and transmission of this type of disease remains a potential risk. It is therefore important for dentists to be aware of these diseases, to identify high-risk patients by obtaining an adequate clinical history, and to know the appropriate procedures to be followed.</div>
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<Abstract><AbstractText>Prions are normal proteins present in all mammals, especially in the central nervous system (CNS) and lymphoreticular tissue. Their transformation into a highly infectious molecule gives rise to a group of diseases known as transmissible spongiform encephalopathies (TSEs), which cause vacuolar degeneration of gray matter and produce a fatal neurodegenerative disorder. Prion diseases have attracted considerable attention in recent years, and this review of the literature was designed to determine their implications for dentistry, studying the possibility of cross-transmission in the dental office and describing their oral manifestations. The main oral manifestations are dysphagia, dysarthria, paresthesias, dysesthesias, and dysgeusia. The most frequently involved oral tissues are the trigeminal ganglion, posterior third of the tongue, tonsils, and, much less commonly, alveolar nerves, gingiva, and salivary glands. Although no contagion has been reported in the dental setting to date, prions resist the usual dental sterilization systems and transmission of this type of disease remains a potential risk. It is therefore important for dentists to be aware of these diseases, to identify high-risk patients by obtaining an adequate clinical history, and to know the appropriate procedures to be followed.</AbstractText>
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